Xianglin Shi Selected Research

chromium hexavalent ion

10/2019	Retraction: Activation of epidermal growth factor receptor/p38/hypoxia-inducible factor-1 α is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium.
4/2018	Oxidative Stress and Metabolic Reprogramming in Cr(VI) Carcinogenesis.
1/2018	Investigating the Role of Mitochondrial Respiratory Dysfunction during Hexavalent Chromium-Induced Lung Carcinogenesis.
1/2018	Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation.
8/2017	Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway.
1/2017	Protection from Cr(VI)-induced malignant cell transformation and tumorigenesis of Cr(VI)-transformed cells by luteolin through Nrf2 signaling.
8/2016	Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling.
1/2016	Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells.
1/2016	Activation of Epidermal Growth Factor Receptor/p38/Hypoxia-inducible Factor-1α Is Pivotal for Angiogenesis and Tumorigenesis of Malignantly Transformed Cells Induced by Hexavalent Chromium.
1/2015	Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development.

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Xianglin Shi Research Topics

Disease

82	Neoplasms (Cancer) 01/2020 - 08/2002
72	Carcinogenesis 10/2019 - 02/2002
15	Inflammation (Inflammations) 01/2020 - 05/2002
15	Lung Neoplasms (Lung Cancer) 01/2018 - 01/2004
14	Hypoxia (Hypoxemia) 10/2019 - 05/2002
11	Neoplasm Metastasis (Metastasis) 05/2016 - 08/2003
11	Breast Neoplasms (Breast Cancer) 01/2016 - 08/2003
9	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 10/2003
5	Leukemia 01/2012 - 01/2006
5	Fibrosis (Cirrhosis) 07/2011 - 04/2003
5	Pneumonia (Pneumonitis) 10/2010 - 01/2002
5	Ovarian Neoplasms (Ovarian Cancer) 04/2007 - 08/2004
4	Colonic Neoplasms (Colon Cancer) 01/2020 - 08/2006
4	Lung Diseases (Lung Disease) 08/2017 - 05/2002
4	Colorectal Neoplasms (Colorectal Cancer) 05/2016 - 07/2012
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2016 - 07/2004
4	Skin Neoplasms (Skin Cancer) 06/2013 - 07/2004
4	Neuroblastoma 11/2012 - 03/2008
4	Carcinoma (Carcinomatosis) 06/2011 - 08/2002
3	Macular Degeneration (Age-Related Maculopathy) 01/2020 - 11/2010
3	Adenocarcinoma of Lung 11/2015 - 06/2006
3	Insulin Resistance 06/2008 - 10/2007
3	Lung Injury 02/2003 - 02/2002
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 02/2010
2	Adenocarcinoma 01/2016 - 10/2011
2	Genomic Instability 12/2012 - 04/2005
2	Intellectual Disability (Idiocy) 10/2011 - 05/2009
2	Fetal Alcohol Spectrum Disorders 10/2011 - 05/2009
2	Necrosis 06/2010 - 04/2005
2	Hypersensitivity (Allergy) 09/2009 - 01/2009

Drug/Important Bio-Agent (IBA)

28	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2018 - 02/2002
23	ArsenicIBA 01/2020 - 08/2003
22	chromium hexavalent ionIBA 10/2019 - 05/2002
20	Proteins (Proteins, Gene)FDA Link 01/2020 - 08/2003
18	CarcinogensIBA 08/2017 - 02/2002
17	Ethanol (Ethyl Alcohol)IBA 01/2020 - 08/2003
17	AntioxidantsIBA 04/2018 - 05/2002
16	MetalsIBA 04/2018 - 04/2002
14	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 05/2002
10	NickelIBA 10/2018 - 12/2003
8	CatalaseIBA 08/2017 - 05/2002
7	Transcription Factors (Transcription Factor)IBA 01/2017 - 05/2002
7	Silicon Dioxide (Silica)FDA LinkGeneric 07/2011 - 02/2002
6	Pharmaceutical PreparationsIBA 01/2020 - 08/2006
6	Hypoxia-Inducible Factor 1IBA 01/2020 - 11/2002
6	NF-kappa B (NF-kB)IBA 11/2004 - 02/2002
5	EnzymesIBA 04/2018 - 12/2012
5	CateninsIBA 05/2016 - 10/2011
5	arseniteIBA 08/2010 - 02/2002
5	polypeptide 1 70kD ribosomal protein S6 kinaseIBA 07/2007 - 01/2004
4	ErbB Receptors (EGF Receptor)IBA 10/2019 - 11/2006
4	CadmiumIBA 10/2018 - 10/2012
4	Heavy MetalsIBA 01/2017 - 11/2005
4	LuteolinIBA 01/2017 - 06/2006
4	ChemokinesIBA 10/2016 - 06/2012
4	ApigeninIBA 10/2013 - 09/2005
4	CaspasesIBA 01/2012 - 04/2005
4	Insulin (Novolin)FDA Link 01/2012 - 01/2007
4	Sirolimus (Rapamycin)FDA Link 07/2007 - 08/2004
4	Free RadicalsIBA 11/2005 - 05/2002
3	QuercetinIBA 08/2017 - 12/2010
3	CytokinesIBA 10/2016 - 05/2002
3	Small Interfering RNA (siRNA)IBA 01/2016 - 07/2005
3	Phosphotransferases (Kinase)IBA 04/2015 - 01/2009
3	FlavonoidsIBA 10/2013 - 04/2007
3	Superoxide DismutaseIBA 09/2013 - 06/2008
3	Protein Kinases (Protein Kinase)IBA 01/2012 - 05/2003
3	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2012 - 10/2003
3	Mitogen-Activated Protein KinasesIBA 05/2011 - 01/2004
3	ResveratrolIBA 10/2007 - 10/2003
3	AsbestosIBA 07/2005 - 05/2002
3	Biological ProductsIBA 08/2004 - 05/2002
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 08/2004 - 05/2002
2	Verteporfin (Visudyne)FDA Link 01/2020 - 01/2018
2	LipidsIBA 04/2018 - 11/2010
2	Amino Acids FDA Link 04/2018 - 02/2007
2	sulforaphaneIBA 01/2018 - 09/2008
2	Oxygen (Dioxygen)IBA 01/2018 - 01/2012
2	PolyphenolsIBA 01/2017 - 11/2010
2	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2017 - 06/2007
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 05/2016 - 06/2012
2	p38 Mitogen-Activated Protein KinasesIBA 01/2016 - 05/2003
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2015 - 10/2014
2	LigandsIBA 01/2015 - 10/2013
2	Dinoprostone (PGE2)FDA Link 10/2014 - 06/2006
2	cyanidin-3-O-beta-glucopyranosideIBA 10/2014 - 10/2010
2	quercitrinIBA 06/2013 - 01/2010
2	ChromiumIBA 07/2012 - 01/2004
2	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 01/2012 - 01/2012
2	AgarIBA 10/2011 - 01/2008
2	Cytochromes c (Cytochrome c)IBA 05/2011 - 01/2006
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 08/2010 - 08/2004
2	hydroxide ionIBA 02/2010 - 04/2005
2	Glycogen Synthase Kinase 3 betaIBA 09/2009 - 04/2008
2	Histones (Histone)IBA 07/2009 - 02/2009
2	JNK Mitogen-Activated Protein KinasesIBA 02/2009 - 11/2004
2	Messenger RNA (mRNA)IBA 12/2008 - 07/2005
2	Biomarkers (Surrogate Marker)IBA 12/2008 - 11/2005
2	A-factor (Streptomyces)IBA 10/2008 - 01/2006

Therapy/Procedure

10	Therapeutics 01/2019 - 06/2006